According to data released by the US Food and Drug Administration (FDA) on the abortion pill, mifepristone, more than 1.2 million unborn children have lost their lives because of it, but even more stunningly, thousands of women have been injured and this includes more than a dozen who have died in the United States alone.
Just after the approval of mifepristone during the Clinton administration, the FDA released a report in 2006 that showed that more than 1,100 women had been subjected to “adverse effects” after taking mifepristone. Pro-life advocates have waited five years for the FDA to come out with a new report of the adverse effects associated with this drug. This drug seems to continue to kill and injure women all across the globe.
Mifespristone, which is marketed under the trade names Mifeprex and Korlyn, is still known by the name given to it when it was an experimental drug, RU486. Mifepristone is a synthetic steroid drug that binds to the progesterone receptors in cells in the endometrium and prevents the progesterone receptor from receiving signals from progesterone. Because the endometrium requires constant progesterone signaling to maintain itself, mifepristone causes the endometrium to breakdown. It also causes the cervix to soften and induces the release of mo9lecules called prostaglandins. These prostaglandins causes the smooth muscle of the uterus to contract, but mifepristone, also increases the sensitivity of the smooth muscle of the uterus to prostaglandins. The breakdown of the endometrium and the contractions of the uterine smooth muscle cause the embryo to detach. This eventually kills of all sources of progesterone production in the mother’s body, and the embryo dies. Typically, mifepristone is followed by an oral prostaglandin (misoprostol) to increase uterine smooth muscle contraction and expulsion of the dead embryo. Mifepristone is used to terminate pregnancies that are not older than 49 days. The approval of mifepristone did include a Black Box Warning, as required under Subsection H.
There are several excellent articles about this FDA data. Read about it here, here and here. Mifepristone also has caused problems in women all around the world. These data in this report is limited to adverse effects in the United States only.