3D Printed Sugar Network to feed Engineered Organs


A 3-D sugar network to feed bioengineered organs: moldable, biodegradable, and useable. In a word – Sweet!!

Leaders in Pharmaceutical Business Intelligence (LPBI) Group

3D Printed Sugar Network to feed Engineered Organs

Reporter: Irina Robu, PhD

“Tissue engineers have long dreamed of building an organ in a dish. But without vessels running through the tissue, cells in the centre starve and suffocate.

Now, US researchers can build vessels into a cell-containing gel – the beginnings of a thick tissue. Scientists form the gel around a lattice of printed sugar fibres. The fibres dissolve after the gel sets, leaving a network of channels that carry nutrients like blood vessels.

For the past decade, tissue engineers have looked for ways to build a 3D tissue in such a way that vessels are immediately available to feed growing cells. One way to create these vessels uses a tiny silicon template to pattern grooves in a sheet of cell-containing gel. Covering these cut outs with another sheet of engineered tissue creates enclosed channels. While these sheets can be…

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mburatov

Professor of Biochemistry at Spring Arbor University (SAU) in Spring Arbor, MI. Have been at SAU since 1999. Author of The Stem Cell Epistles. Before that I was a postdoctoral research fellow at the University of Pennsylvania in Philadelphia, PA (1997-1999), and Sussex University, Falmer, UK (1994-1997). I studied Cell and Developmental Biology at UC Irvine (PhD 1994), and Microbiology at UC Davis (MA 1986, BS 1984).